Common Medications Can Worsen Depression
(A Country Doctor Reads)
I just read an article with a case vignette about a depressed patient who tolerated propranolol, which as a non selective beta blocker is known to sometimes worsen depression. But when he started taking Coenzyme Q10, he became much worse.
“Individual medications significantly associated with the severity of depressive symptoms included omeprazole, gabapentin, meloxicam, tramadol, ranitidine, baclofen, oxycodone, tizanidine, propranolol, and morphine. There was a dose-dependent effect of PDSS (drugs with potential depressive symptom side effects).”
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